Antithrombin III polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Serpin peptidase inhibitor, clade C(antithrombin), member 1, also known as Antithrombin III(AT3) is the most important inhibitor of thrombin OMBIN III and other coagulation proteinases. This gene is mapped to 1q25.1. The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.

Description:
Rabbit IgG polyclonal antibody for Antithrombin-III (SERPINC1) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
ANT3_HUMAN antibody, Antithrombin antibody, Antithrombin III antibody, Antithrombin-III antibody, AntithrombinIII antibody, AT 3 antibody, AT III antibody, AT3 antibody, AT3D antibody, ATIII antibody, MGC22579 antibody, Serine(or cysteine) proteinase inhibitor clade C(antithrombin) member 1 antibody, Serine cysteine proteinase inhibitor clade C member 1 antibody, Serine proteinase inhibitor clade C member 1 antibody, SERPIN C1 antibody, Serpin peptidase inhibitor clade C(antithrombin) member 1 antibody, SERPINC1 antibody, THPH7 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human Antithrombin III(93-107aa TFYQHLADSKNDNDN), different from the related mouse and rat sequences by one amino acid.A synthetic peptide corresponding to a sequence at the N-terminus of human Antithrombin III(93-107aa TFYQHLADSKNDNDN), different from the related mouse and rat sequences by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.