ANXA6 Polyclonal Antibody

Background:
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described.

Research Area: Cancer, Signal Transduction

Synonyms:
67 kDa calelectrin, Annexin A6, Annexin VI, Annexin VI p68, Annexin-6, AnnexinA6, AnnexinVI, ANX 6, ANX A6, ANX6, ANXA 6, ANXA6, ANXA6, Calcium binding protein p68, Calelectrin, Calphobindin II, Calphobindin-II, CalphobindinII, CBP 68, CBP68, Chromobindin 20, Chromobindin-20, Chromobindin20, CPB II, CPB-II, CPBII, Lipocortin VI, LipocortinVI, p68, p70, Protein III, ProteinIII

Immunogen: Recombinant Rat Annexin A6 protein

Swissprot: P48037

Calculated MW: 76 kDa
Observed MW: 72 kDa

Purification Method: Affinity Purification

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Concentration: 1 mg/mL
Dilution: WB 1:1000-1:4000 IHC1:100-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.