AP2A1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined.

Synonyms: ADTAA, AP2-ALPHA, CLAPA1

Cellular Location: Cell membrane Cytoplasmic side Membrane Peripheral membrane protein coated pit

Immunogen:
Recombinant protein of human AP2A1

Gene Symbol: AP2A1

Gene ID: 160

Swiss prot: O95782

Calculated MW: 108kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.