Apaf-1 polyclonal, anti-human, mouse, rat, rabbit, primate, bovine, horse antibody
€295.00
In stock
SKU
AC-ABV10011-100
Catalog Number: AC-ABV10011-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
During apoptosis, Apaf-1 (apoptosis protease activating factor 1) binds to cytochrome c (Apaf-2), a reaction that requires dATP, and this leads to the formation of a large multimeric complex. The complex recruits pro-caspase-9, and activates caspase-9 (Apaf-3). Activated caspase-9 in turn cleaves and activates caspase-3, one of the proteases responsible for the proteolytic cleavage of many key proteins in apoptosis. Apaf-1 is ubiquitously expressed in human tissues.
Other Names:
APAF1, CED4, DKFZp781B1145, KIAA0413
Primary Accession: O14727
Gene Name: APAF1 (HGNC:576)
Gene ID: 317
Concentration (mg/ml): 0.2 mg/ml
During apoptosis, Apaf-1 (apoptosis protease activating factor 1) binds to cytochrome c (Apaf-2), a reaction that requires dATP, and this leads to the formation of a large multimeric complex. The complex recruits pro-caspase-9, and activates caspase-9 (Apaf-3). Activated caspase-9 in turn cleaves and activates caspase-3, one of the proteases responsible for the proteolytic cleavage of many key proteins in apoptosis. Apaf-1 is ubiquitously expressed in human tissues.
Other Names:
APAF1, CED4, DKFZp781B1145, KIAA0413
Primary Accession: O14727
Gene Name: APAF1 (HGNC:576)
Gene ID: 317
Concentration (mg/ml): 0.2 mg/ml
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