APBA2 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Area: Neuroscience

Synonyms:
Adapter protein X11beta, Amyloid beta A4 precursor protein-binding family A member 2, APBA2, APBA2, D15S1518E, HsT16821, LIN 10, MGC:14091, MGC99508, Mint 2, Mint-2, MINT2, Neuron-specific X11L protein, Neuronal Munc18-1-interacting protein 2, Phosphotyrosine binding/interacting domain (PTB) bearing protein, X11 beta, X11 like protein, X11l

Immunogen: Synthetic peptide of human APBA2

Swissprot: Q99767
Gene Accession: NP_001123886

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-31512/sc-8520/sc-30135/sc-28968