APC polyclonal (Center), anti-mouse
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In stock
SKU
AC-AP19274c
Catalog Number: AC-AP19274c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB37442
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB37442
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product
Other Names:
Adenomatous polyposis coli protein, Protein APC, Deleted in polyposis 25, APC, DP25
Target/Specificity:
This APC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1148-1176 amino acids from the Central region of human APC.
Antigen Region:
1148-1176
Antigen Type: Synthetic Peptide
Gene Name: APC (HGNC:583)
Gene ID: 324
Primary Accession: P25054
NCBI Accession: NP_000029.2;NP_001120982.1
Other Accession: NP_000029.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product
Other Names:
Adenomatous polyposis coli protein, Protein APC, Deleted in polyposis 25, APC, DP25
Target/Specificity:
This APC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1148-1176 amino acids from the Central region of human APC.
Antigen Region:
1148-1176
Antigen Type: Synthetic Peptide
Gene Name: APC (HGNC:583)
Gene ID: 324
Primary Accession: P25054
NCBI Accession: NP_000029.2;NP_001120982.1
Other Accession: NP_000029.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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