Apelin polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Apelin is a neuropeptide expressed in the supraoptic and paraventricular nuclei that acts on specific receptors located on vasopressinergic neurons. The apelin gene to Xq25-q26.3 based on sequence similarity between the apelin sequence and a chromosome X PAC clone. This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.

Description:
Rabbit IgG polyclonal antibody for Apelin (APLN) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
AGTRL1 ligand antibody, APEL antibody, APEL_HUMAN antibody, Apelin-13 antibody, APJ endogenous ligand antibody, Apln antibody, XNPEP2 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Apelin(60-77aa RKFRRQRPRLSHKGPMPF), identical to the related rat and mouse sequences.A synthetic peptide corresponding to a sequence at the C-terminus of human Apelin(60-77aa RKFRRQRPRLSHKGPMPF), identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.