APEX1 antibody (clone 4D1), anti-human
€435.00
In stock
SKU
AC-AT1160a
Catalog Number: AC-AT1160a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: E
Request Information AC-AT1160a">Request Information
Background:
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
Other Names:
DNA-(apurinic or apyrimidinic site) lyase, 31--, APEX nuclease, APEN, Apurinic-apyrimidinic endonuclease 1, AP endonuclease 1, APE-1, REF-1, Redox factor-1, DNA-(apurinic or apyrimidinic site) lyase, mitochondrial, APEX1, APE, APE1, APEX, APX, HAP1, REF1
Antigen Type:
Recombinant Protein
Gene Name: APEX1
Gene ID: 328
NCBI Accession: NP_001231178.1;NP_001632.2;NP_542379.1;NP_542380.1
Primary Accession: P27695
Other Accession: NM_001641
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
Other Names:
DNA-(apurinic or apyrimidinic site) lyase, 31--, APEX nuclease, APEN, Apurinic-apyrimidinic endonuclease 1, AP endonuclease 1, APE-1, REF-1, Redox factor-1, DNA-(apurinic or apyrimidinic site) lyase, mitochondrial, APEX1, APE, APE1, APEX, APX, HAP1, REF1
Antigen Type:
Recombinant Protein
Gene Name: APEX1
Gene ID: 328
NCBI Accession: NP_001231178.1;NP_001632.2;NP_542379.1;NP_542380.1
Primary Accession: P27695
Other Accession: NM_001641
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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