APG4B polyclonal, anti-human, mouse, rat

Background:
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Synonyms: AUTL1, KIAA0943, ATG4B, Hapg4b

Cellular Location: Cytoplasm Nucleus

Immunogen:
A synthetic peptide of human APG4B

Gene Symbol: APG4B

Gene ID: 23192

Swiss prot: Q9Y4P1

Calculated MW: 40kDa

Recommended dilution:
WB 1:2000-5000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.