Apg7 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Autophagy-related protein 7 is a protein that in humans is encoded by the ATG7 gene. It is mapped to 3p25.3. This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein also shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes. ATG7 is essential for the Apg12 conjugation system that mediates membrane fusion in autophagy. It is found that when nutrients are limited, ATG7 can regulate p53-dependent cell cycle and cell death pathways.

Description:
Rabbit IgG polyclonal antibody for Ubiquitin-like modifier-activating enzyme ATG7 (ATG7) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
1810013K23Rik antibody, Apg 7 antibody, APG7 autophagy 7 like antibody, APG7 autophagy 7-like (S. cerevisiae) antibody, APG7 like antibody, APG7, S. cerevisiae, homolog of antibody, APG7-like antibody, APG7L antibody, ATG 7 antibody, ATG12-activating enzyme E1 ATG7 antibody, atg7 antibody, ATG7 autophagy related 7 homolog (S. cerevisiae) antibody, ATG7 autophagy related 7 homolog antibody, Atg7l antibody, Autophagy 7, S. cerevisiae, homolog of antibody, Autophagy related protein 7 antibody, Autophagy-related 7 (yeast) antibody, Autophagy-related protein 7 antibody, DKFZp434N0735 antibody, GSA 7 antibody, GSA7 antibody, hAGP7 antibody, Ubiquitin activating enzyme E1 like protein antibody, Ubiquitin-activating enzyme E1-like protein antibody, Ubiquitin-like modifier-activating enzyme ATG7 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Apg7 (673-703aa HSFLEDLTGLTLLHQETQAAEIWDMSDDETI), different from the related mouse and rat sequences by two amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.