APH1A polyclonal, anti-human

Background:
APH1 is a multipass transmembrane protein that interacts with presenilin (see PSEN1; MIM 104311) and nicastrin (APH2; MIM 605254) as a functional component of the gamma-secretase complex. The gamma-secretase complex is required for the intramembrane proteolysis of a number of membrane proteins, including the amyloid-beta precursor protein (APP; MIM 104760) and Notch (MIM 190198).

Other Names:
Gamma-secretase subunit APH-1A, APH-1a, Aph-1alpha, Presenilin-stabilization factor, APH1A, PSF

Antigen Types:
Synthetic Peptide

Gene Name:
APH1A
Gene ID:
51107
Primary Accession: Q96BI3
Other Accession: NP_057106;51107;