APH1A polyclonal (N-term), anti-mouse

APH1A polyclonal (N-term), anti-mouse

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In stock
SKU
AC-AP19161A
Catalog Number: AC-AP19161A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB39321
Applications: WB
Datasheet

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Background:
APH1 is a multipass transmembrane protein that interacts with presenilin (see PSEN1; MIM 104311) and nicastrin (APH2; MIM 605254) as a functional component of the gamma-secretase complex. The gamma-secretase complex is required for the intramembrane proteolysis of a number of membrane proteins, including the amyloid-beta precursor protein (APP; MIM 104760) and Notch (MIM 190198).

Other Names:
Gamma-secretase subunit APH-1A, APH-1a, Aph-1alpha, Presenilin-stabilization factor, APH1A, PSF

Target/Specificity:
This APH1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human APH1A.

Antigen Region:
41-70

Antigen Type: Synthetic Peptide

Gene Name: APH1A
Gene ID: 51107
Primary Accession: Q96BI3
NCBI Accession: NP_001071096.1;NP_001230700.1;NP_001230701.1;NP_057106.2
Other Accession: Q8BVF7; NP_057106.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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