API5 Polyclonal Antibody

Background:
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Research Area: Cancer, Cell Biology

Synonyms:
AAC 11, AAC-11, AAC11, Antiapoptosis clone 11 protein, API 5, API-5, api5, API5 like 1, API5, API5L1, Apoptosis inhibitor 5, Cell migration inducing gene 8 protein, Cell migration-inducing gene 8 protein, Fibroblast growth factor 2 interacting factor 2, Fibroblast growth factor 2-interacting factor, FIF, MIG 8, MIG8, Migration inducing protein MIG8, Protein XAGL

Immunogen: Synthetic peptide of human API5

Swissprot: Q9BZZ5
Gene Accession: NP_001136402

Calculated MW: 59 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 1.1 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-167094/sc-167096