APIP polyclonal (Center), anti-human

APIP polyclonal (Center), anti-human

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In stock
SKU
AC-AP22073c
Catalog Number: AC-AP22073c
Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB55049
Applications: WB, IHC-P
Datasheet

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Background:
Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.

Other Names:
Methylthioribulose-1-phosphate dehydratase {ECO:0000255|HAMAP-Rule:MF_03116}, MTRu-1-P dehydratase {ECO:0000255|HAMAP-Rule:MF_03116}, 4.2.1.109 {ECO:0000255|HAMAP-Rule:MF_03116}, APAF1-interacting protein {ECO:0000255|HAMAP-Rule:MF_03116}, hAPIP, APIP {ECO:0000255|HAMAP-Rule:MF_03116}

Target/Specificity:
This APIP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 111-142 amino acids from the Central region of human APIP.

Antigen Type: Synthesized Peptide

Gene Name: APIP {ECO:0000255|HAMAP-Rule:MF_03116}
Gene ID: 51074
Primary Accession: Q96GX9
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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