APOA1 polyclonal, anti-human, mouse, rat

Background:
Apolipoproteins are protein components of plasma lipoproteins. The human apoA-I gene encodes a single chain, 243 amino acid protein which promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. It can function as a cofactor for lecithin cholesterolacyltransferase (LCAT), which is responsible for the formation of most plasma cholesteryl esters. The human apoA-II gene encodes the second most abundant protein of HDL particles, where it influences plasma levels of free fatty acids (FFA). The human apoA-IV gene encodes a 396 amino acid preprotein, which after proteolytic processing is secreted from the intestine in association with chylomicron particles. ApoA-IV is a potent activator of LCAT in vitro. The human apoA-V gene encodes a 366 amino acid protein that is believed to be an important determinant of plasma triglyceride levels.

Alternative Name:
Apo-AI, ApoA-I, Apolipoprotein A1, ProapoA-I, APOA1, Apo-AI, ApoA I, ApoA-I, APOA1, APOA1, Apolipoprotein A-I(1-242), Apolipoprotein A1, Apolipoprotein AI, Brp14, Ltw1, Lvtw1, Sep1, Sep2,

Application Dilution:
WB:1:1,000-1:2,000
ICC:1:50-1:200
IHC:1:50-1:100
FC:1:50-1:100

Specificity: APOA1 polyclonal antibody detects endogenous levels of APOA1 protein.

Immunogen:
Peptide

MW: 27 kDa

Swiss-Prot: P02647(Human) Q00623(Mouse) P04639(Rat)

Purification & Purity:
Peptide affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.