Apobec1 polyclonal (N-term), anti-human, mouse

Apobec1 polyclonal (N-term), anti-human, mouse

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In stock
SKU
AC-AP1352a
Catalog Number: AC-AP1352a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1746
Applications: WB, IHC-P
Datasheet

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Background:
APOBEC1 is involved in the production of apolipoprotein B (apoB)-48 from apoB-100. The gene spans 18 kb and contains five exons, all of which are translated. Alternative splicing produces a variant transcript that lacks exon 2 and encodes a novel 36-amino acid peptide. The exon 2-skipped transcript accounts for approximately 50% of APOBEC1 mRNA in the adult small intestine and up to 90% of APOBEC1 mRNA in the developing gut. Exon 2-skipping may thus be a quantitatively important mechanism for regulating the expression of this gene in the gastrointestinal tract.

Other Names:
C->U-editing enzyme APOBEC-1, 354-, Apolipoprotein B mRNA-editing enzyme 1, HEPR, APOBEC1

Target/Specificity:
This Apobec1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human Apobec1.

Antigen Region:
7-36

Antigen Type: Synthetic Peptide

Gene Name: APOBEC1 (HGNC:604)
Gene ID: 339
Primary Accession: P41238
NCBI Accession: NP_001635.2
Other Accession: NP_001635
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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