APOBEC3A Polyclonal Antibody

Background:
apolipoprotein B mRNA editing enzyme catalytic subunit 3A(APOBEC3A) Homo sapiens This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided b

Alternative Names:
APOBEC3A, Probable DNA dC->dU-editing enzyme APOBEC-3A, Phorbolin-1

Immunogen: The antiserum was produced against synthesized peptide derived from human APOBEC3A. AA range:27-76

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 26

GeneID: APOBEC3A

Storage: -20°C/1 year

NOTE: For Research Use Only