APOBEC3B polyclonal, anti-human
€295.00
In stock
SKU
K005987P
Catalog Number: K005987P
Size: 100 μl
Other size: 50 μl
Isotype: Rabbit IgG
Applications: WB
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Questions? Contact us!
Size: 100 μl
Other size: 50 μl
Isotype: Rabbit IgG
Applications: WB
Request Manual
Questions? Contact us!
Background:
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms: A3B, APOBEC1L, ARCD3, ARP4, DJ742C19.2, PHRBNL, bK150C2.2
Cellular Location: Nucleus
Immunogen:
Recombinant protein of human APOBEC3B
Gene Symbol: APOBEC3B
Gene ID: 9582
Swiss prot: Q9UH17
Calculated MW: 46kDa
Recommended dilution:
WB 1:200-1000
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms: A3B, APOBEC1L, ARCD3, ARP4, DJ742C19.2, PHRBNL, bK150C2.2
Cellular Location: Nucleus
Immunogen:
Recombinant protein of human APOBEC3B
Gene Symbol: APOBEC3B
Gene ID: 9582
Swiss prot: Q9UH17
Calculated MW: 46kDa
Recommended dilution:
WB 1:200-1000
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
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