APOC3 polyclonal, anti-human

Background:
Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion, extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners.

Alternative Name:
Apo-CIII, ApoC-III, APOC3, APO C3, Apo CIII, Apo-CIII, APOC 3, ApoC III, ApoC-III, APOC3, APOC3, ApoCIII, Apolipoprotein C III, Apolipoprotein C-III, Apolipoprotein C3, ApolipoproteinCIII, MGC150353,

Application Dilution:
WB:1:500-1:2000
IHC:1:50-1:200
FC:1:50-1:100

Specificity: APOC3 polyclonal antibody detects endogenous levels of APOC3 protein.

Immunogen:
Recombinant protein with Human APOC3 aa 1-100.

MW: 11 kDa

Swiss-Prot: P02656(Human)

Purification & Purity:
Protein affinity purified.

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.