APOC3 Polyclonal Antibody

Background:
Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms:
APOC3, APOCIII, HALP2

Immunogen: A synthetic peptide of human APOC3 (NP_000031.1).

Swissprot: P02656
Gene ID: 345

Calculated MW: 10 kDa
Observed MW: 11 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:100-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.