ApoE polyclonal, anti-human, mouse

Background:
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

Synonyms: AD2, APO-E, ApoE4, LDLCQ5, LPG

Cellular Location: Secreted

Immunogen:
A synthetic peptide of human ApoE

Gene Symbol: ApoE

Gene ID: 348

Swiss prot: P02649

Calculated MW: 36kDa

Recommended dilution:
WB 1:1000-3000, IHC 1:50-200, IF 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.