APOE Polyclonal Antibody

Background:
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

Research Area: Cancer, Cardiovascular, Metabolism, Developmental Biology, Neuroscience, Signal Transduction, Stem Cells

Synonyms:
APOE, AD2, APO-E, ApoE4, LDLCQ5, LPG, ApoE

Immunogen: A synthetic peptide of human APOE (NP_000032.1).

Swissprot: P02649
Gene ID: 348

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:200 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.