Apolipoprotein A1, APOA1 (clone N47-7), anti-human

Apolipoprotein A1, APOA1 (clone N47-7), anti-human

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In stock
SKU
BMA1006
Catalog Number: BMA1006
Size: 100 μg
Isotype: Mouse IgG1
Reactivity: human
Application(s): WB, IHC-P, ICC, Flow-Cyt
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Background:
Apolipoprotein A-I (APOA1) is the major protein component of high density lipoprotein (HDL) in plasma.[1]Chylomicrons secreted from the intestinal enterocyte also contain ApoA1 but it is quickly transferred to HDL in the bloodstream.[2]It was composed of an N-terminal 4-helix bundle with a hydrophobic core and 2 C-terminal helices.[3]It has an approximate molecular weight of 28 KDa. A G/A polymorphism in the promoter of the ApoA-I gene has been associated with the age at which patients presented with Alzheimer disease.[4]Protection from Alzheimer disease by ApoA1 may rely on a synergistic interaction with alpha-tocopherol.[5]

Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to the region of human APOA1.

Recommended Application:
Western Blot, WB (1:200-1:500); Immunohistochemistry, IHC-P(1:20-1:100); Immunocytochemistry, ICC (1:20-1:100); Flow Cytometry, Flow-Cyt (1:20-1:50)

Product Form: Liquid

Purification: Protein A purified

Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.

Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
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