Apolipoprotein E polyclonal, anti-human

Quantity: 100 µg

Background:
APOE is also known as AD2 or LPG. The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple transcript variants.

Description:
Rabbit IgG polyclonal antibody for Apolipoprotein E (APOE) detection. Tested with WB, IHC-P in Human.

Synonyms:
AD2 antibody, Alzheimer disease 2 antibody, Apo E antibody, Apo-E antibody, ApoE antibody, APOE_HUMAN antibody, APOEA antibody, Apolipoprotein E antibody, Apolipoprotein E3 antibody, ApolipoproteinE antibody, Apoprotein antibody, LDLCQ5 antibody, LPG antibody, MGC1571 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human Apolipoprotein E recombinant protein (Position: K19-H317). Human Apolipoprotein E shares 73% and 72% amino acid (aa) sequence identity with mouse and rat Apolipoprotein E, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.