Apolipoprotein J polyclonal, anti-human

Quantity: 100 µg

Background:
Clusterin (apolipoprotein J) is a 75 - 80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. In humans, clusterin is encoded by the CLU gene. This protein has several synonyms: dimeric acidic glycoprotein (DAG protein), testosterone repressed prostate message-2 (TRPM-2), sulfated glycoprotein-2 (SGP-2) and complement lysis inhibitor (CLI). Clusterin was mapped to mouse chromosome 14. Clusterin is a ubiquitously expressed molecule thought to influence a variety of processes including cell death. In the brain, it accumulates in dying neurons following seizures and hypoxic-ischemic (H-I) injury. clusterin may be a new therapeutic target to modulate non-caspase-dependent neuronal death following acute brain injury.

Description:
Rabbit IgG polyclonal antibody for Clusterin (CLU) detection. Tested with WB, IHC-P, ELISA in Human.

Synonyms:
40 antibody, AAG 4 antibody, AAG4 antibody, Aging associated protein 4 antibody, Aging-associated gene 4 protein antibody, AI893575 antibody, APO J antibody, Apo-J antibody, APOJ antibody, ApoJalpha antibody, ApoJbeta antibody, Apolipoprotein J antibody, ApolipoproteinJ antibody, CLI antibody, CLU antibody, CLU1 antibody, CLU2 antibody, CLUS_HUMAN antibody, Clusterin alpha chain antibody, clusterin antibody, Clusterin beta chain antibody, Clusterin precursor antibody, Complement associated protein SP 40 40 antibody, Complement associated protein SP 40 antibody, Complement associated protein SP40 antibody, Complement cytolysis inhibitor a chain antibody, Complement cytolysis inhibitor antibody, Complement cytolysis inhibitor b chain antibody, Complement lysis inhibitor antibody, Complement-associated protein SP-40 antibody, D14Ucla3 antibody, Dimeric acid glycoprotein antibody, Glycoprotein 80 antibody, Glycoprotein III antibody, GP80 antibody, Ku70-binding protein 1 antibody, KUB 1 antibody, KUB1 antibody, MGC24903 antibody, NA1/NA2 antibody, RATTRPM2B antibody, SGP 2 antibody, SGP2 antibody, SP 40 antibody, SP40 antibody, Sufated glycoprotein 2 antibody, Sugp-2 antibody, Sulfated glycoprotein 2 antibody, Testosterone repressed prostate message 2 antibody, Testosterone-repressed prostate message 2 antibody, TRPM 2 antibody, TRPM-2 antibody, TRPM2 antibody, TRPM2B antibody, Trpmb antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E. coli-derived human Apolipoprotein J recombinant protein (Position: S228-E449). Human Apolipoprotein J shares 76.1 % and 75.2 % amino acid (aa) sequence identity with mouse and rat Apolipoprotein J, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P, ELISA

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.