APP (clone 1B11F3), anti-human

APP (clone 1B11F3), anti-human

€0.00
In stock
SKU
BT-MCA3013
Catalog Number: BT-MCA3013
Size(s): 50μL, 100μL
Isotype: Mouse IgG2a
Reactivity: human
Application(s): IHC
Datasheet
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Background:
Amyloid precursor protein(APP),with 32-amino acid protein (about 35 kDa), is part of a super-family of transmembrane and secreted proteins. It appears to have a number of roles, including regulation of haemostasis and mediation of neuroprotection. APP undergoes alternative splicing, resulting in several isoforms . Proteolytic cleavage of amyloid precursor protein leads to the formation of the 4 kDa amyloid beta/A4 protein, which is present in human platelets. APP is also involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer patients.

Research Area: Neuroscience, Signal Transduction

Synonyms: APP

Immunogen: Purified recombinant fragment of APP expressed in E. Coli.

Formulation: Ascitic fluid containing 0.03% sodium azide.

Storage:
4°C|-20°C for long term storage
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