APP(CT) polyclonal, anti-human, mouse, rat antibody
€355.00
In stock
SKU
AC-ABV10792-100
Catalog Number: AC-ABV10792-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC, E
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC, E
Datasheet
Request Information
Background:
Accumulation of the amyloid-beta peptide (Abeta) in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. The beta-amyloid protein precursor (APP) is cleaved by beta-secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for gamma-secretase to generate the 4 kDa amyloid-beta peptide (Abeta), which is deposited in the brains of all suffers of Alzheimer's disease.
Other Names:
amyloid-b-peptide, amyloid beta peptide, Amyloid beta A4 protein, Alzheimer disease amyloid protein, ABPP, APPI, Cerebral vascular amyloid peptide,
Primary Accession: P05067
Gene Name: APP (HGNC:620)
Gene ID: 351
Concentration (mg/ml): 1 mg/ml
Accumulation of the amyloid-beta peptide (Abeta) in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. The beta-amyloid protein precursor (APP) is cleaved by beta-secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for gamma-secretase to generate the 4 kDa amyloid-beta peptide (Abeta), which is deposited in the brains of all suffers of Alzheimer's disease.
Other Names:
amyloid-b-peptide, amyloid beta peptide, Amyloid beta A4 protein, Alzheimer disease amyloid protein, ABPP, APPI, Cerebral vascular amyloid peptide,
Primary Accession: P05067
Gene Name: APP (HGNC:620)
Gene ID: 351
Concentration (mg/ml): 1 mg/ml
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