APPL polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
DCC-interacting protein 13-alpha(APPL1) is a protein that in humans is encoded by the APPL1 gene. The APPL1 gene is mapped to 3q21.1-p13.3. It is said to contain 709 amino acids and share 54% amino acid identity with APPL2. APPL is highly expressed in skeletal muscle, heart, ovary, and pancreas, tissues in which AKT2 mRNA is abundant. It has been regarded as an adaptor that may tether inactive AKT2 to the PI3K in the cytoplasm and thereby may expedite recruitment of AKT2 and PI3K to the cell membrane upon mitogenic stimulation.

Description:
Rabbit IgG polyclonal antibody for DCC-interacting protein 13-alpha (APPL1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
Adapter protein containing PH domain antibody, Adaptor Protein Containing pH Domain antibody, Adaptor protein containing pH domain PTB domain and leucine zipper motif 1 antibody, Adaptor protein containing pH domain PTB domain and leucine zipper motif antibody, AKT2 INTERACTOR antibody, APPL 1 antibody, APPL1 antibody, DCC interacting protein 13 alpha antibody, DCC-interacting protein 13-alpha antibody, DIP 13 alpha antibody, DIP13 alpha antibody, Dip13-alpha antibody, DIP13alpha antibody, DP13A_HUMAN antibody, KIAA1428 antibody, PTB domain and leucine zipper motif 1 antibody, PTB Domain and Leucine Zipper Motif antibody, Signaling adaptor protein DIP13alpha antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human APPL(138-158aa NDHDAAINRYSRLSKKRENDK), identical to the related mouse and rat sequences.A synthetic peptide corresponding to a sequence at the N-terminus of human APPL(138-158aa NDHDAAINRYSRLSKKRENDK), identical to the related mouse and rat sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.