APPL1 polyclonal, anti-human, mouse

Background:
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.

Synonyms: APPL1, APPL, DIP13alpha, MODY14, DCC-interacting protein 13-alpha

Cellular Location: Nucleus Cytoplasm  

Immunogen:
A synthetic peptide of human APPL1

Gene Symbol: APPL1

Gene ID: 26060

Swiss prot: Q9UKG1

Calculated MW: 79kDa

Recommended dilution:
WB 1:5000-8000, IHC 1:100-300,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.