APPL1 Polyclonal Antibody

Background:
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.

Research Area: Cancer, Cell Biology, Developmental Biology, Neuroscience, Signal Transduction

Synonyms:
Adapter protein containing PH domain, Adaptor Protein Containing pH Domain, Adaptor protein containing pH domain PTB domain and leucine zipper motif 1, Adaptor protein containing pH domain PTB domain and leucine zipper motif, Adaptor protein phosphotyrosine interacting with PH domain and leucine zipper 1, AKT2 INTERACTOR, APPL 1, Appl1, DCC interacting protein 13 alpha, DCC-interacting protein 13-alpha, DIP 13 alpha, DIP13 alpha, Dip13-alpha, DIP13alpha, DP13A, KIAA1428, PTB domain and leucine zipper motif 1, PTB Domain and Leucine Zipper Motif, Signaling adaptor protein DIP13alpha

Immunogen: Recombinant protein of human APPL1

Swissprot: Q9UKG1
Gene Accession: BC028599

Calculated MW: 80 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-55063/sc-55065/sc-67402