APPL1 Polyclonal Antibody

Background:
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.

Research Area: Cancer, Cell Biology, Developmental Biology, Neuroscience, Signal Transduction

Synonyms:
APPL1, APPL, DIP13alpha, MODY14

Immunogen: Recombinant fusion protein of human APPL1 (NP_036228.1).

Swissprot: Q9UKG1
Gene ID: 26060

Calculated MW: 79 kDa
Observed MW: 95 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.