AQP1 polyclonal, anti-human, mouse, rat

Background:
Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of Aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most Aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation and the secretion and reabsorption of cerebrospinal fluid and aqueous humor. AQP1 is an integral membrane protein expressed in erythrocytes and renal tubule cells.

Alternative Name:
AQP-1, AQP1, AQP 1, AQP CHIP, AQP-1, AQP1, AQP1, aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group), aquaporin 1 (Colton blood group), Aquaporin CHIP, Aquaporin-1, Aquaporin-CHIP, Aquaporin1, Channel forming integral protein 28kDa, Channel like integral membrane protein 28 kDa, CHIP 28, CHIP28, CO, Colton blood group, Growth factor induced delayed early response protein, MGC26324, Urine water channel, Water channel protein CHIP 29, Water channel protein CHIP29, Water channel protein for red blood cells and kidney proximal tubule,

Application Dilution:
WB:1:500-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200

Specificity: AQP1 polyclonal antibody detects endogenous levels of AQP1 protein.

Immunogen:
recombinant protein

MW: 28/35 kDa

Swiss-Prot: P29972(Human) Q02013(Mouse) P29975(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.