AQP2 Polyclonal Antibody

Background:
The basic job of aquaporin 2 is to reabsorb water from the urine while its being removed from the blood by the kidney. Aquaporin 2 is in kidney epithelial cells and usually lies dormant in intracellular vesicle membranes, but when it is needed vasopressin binds to the cell surface vasopressin receptor, activating a signaling pathway that causes the aquaporin 2 containing vesicles to fuse with the plasma membrane so the aquaporin 2 can be used by the cell.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
ADH water channel, AQP 2, AQP CD, AQP-2, AQP-CD, AQP2, AQP2, AQPCD, Aquaporin 2 collecting duct, Aquaporin CD, Aquaporin-2, Aquaporin-CD, Aquaporin2, Aquaporine 2, Collecting duct water channel protein, MGC34501, Water channel aquaporin 2, Water channel protein for renal collecting duct, WCH CD, WCH-CD, WCHCD

Immunogen: Synthetic peptide of human AQP2

Swissprot: P41181
Gene Accession: NP_000477

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-9882/sc-9880/sc-28629