Aquaporin 0 Picoband polyclonal, anti-human, rat
€455.00
In stock
SKU
AC-ABO12497
Catalog Number: AC-ABO12497
Size: 100 µg
Isotype: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µg
Isotype: Rabbit IgG
Applications: WB
Datasheet
Request Information
Description: Rabbit IgG polyclonal antibody for Lens fiber major intrinsic protein(MIP) detection. Tested with WB in Human;Rat.Protein Name: Lens fiber major intrinsic protein
Protein Function:
Water channel (PubMed:24120416). Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core (By similarity). Plays a role in cell-to-cell adhesion and facilitates gap junction coupling (PubMed:24120416). .
Other Names: Lens fiber major intrinsic protein, Aquaporin-0, MIP26, MP26, MIP, AQP0
Subcellular Localization: Cell membrane ; Multi- pass membrane protein . Cell junction, gap junction .
Tissue Specificity: Major component of lens fiber gap junctions.
Gene ID: 4284
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 0 (232-263aa ERLSVLKGAKPDVSNGQPEVTGEPVELNTQAL), different from the related mouse and rat sequences by six amino acids.
Calculated MW: 28122
Purification: Immunogen affinity purified.
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Concentration (mg/ml): Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Protein Function:
Water channel (PubMed:24120416). Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core (By similarity). Plays a role in cell-to-cell adhesion and facilitates gap junction coupling (PubMed:24120416). .
Other Names: Lens fiber major intrinsic protein, Aquaporin-0, MIP26, MP26, MIP, AQP0
Subcellular Localization: Cell membrane ; Multi- pass membrane protein . Cell junction, gap junction .
Tissue Specificity: Major component of lens fiber gap junctions.
Gene ID: 4284
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 0 (232-263aa ERLSVLKGAKPDVSNGQPEVTGEPVELNTQAL), different from the related mouse and rat sequences by six amino acids.
Calculated MW: 28122
Purification: Immunogen affinity purified.
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Concentration (mg/ml): Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
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