Aquaporin 0 polyclonal, anti-mouse, human, rat

Quantity: 100 µg

Background:
Lens fiber major intrinsic protein also called MIP26 or MP26 is a protein that in humans is encoded by the MIP gene. MIP is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. Using 2-color fluorescence in situ hybridization on high-resolution R-banded chromosomes and human genomic DNA clones for MIP as probes, this gene was found that located in close proximity in region 12q13. MIP plays a crucial role in the development of a transparent eye lens. This gene may be responsible for regulating the osmolarity of the lens and interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.

Description:
Rabbit IgG polyclonal antibody for Lens fiber major intrinsic protein (MIP) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
AQP 0 antibody, AQP0 antibody, Aquaporin antibody, Aquaporin0 antibody, Lens fiber major intrinsic protein antibody, LIM 1 antibody, LIM1 antibody, Major intrinsic protein 26kD antibody, Major intrinsic protein of lens fiber antibody, MIP 26 antibody, MIP antibody, MIP26 antibody, MP 26 antibody, MP26 antibody, PALM antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of mouse Aquaporin 0(246-263aa NGQPEGTGEPVELKTQAL), identical to the related rat sequence, and different from the related human sequence by two amino acids.A synthetic peptide corresponding to a sequence at the C-terminus of mouse Aquaporin 0(246-263aa NGQPEGTGEPVELKTQAL), identical to the related rat sequence, and different from the related human sequence by two amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse.
Predicted to work with: human, rat.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.