Aquaporin 4 Polyclonal Antibody

Background:
This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
AQP4, MIWC, WCH4, aquaporin-4

Immunogen: Recombinant fusion protein of human Aquaporin 4 (NP_001641.1).

Swissprot: P55087
Gene ID: 361

Calculated MW: 32 kDa/34 kDa
Observed MW: 35 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.