Aquaporin 5 polyclonal, anti-rat, mouse

Quantity: 100 µg

Background:
Aquaporin 5, also known as AQP5, is a water channel protein. The aquaporins(AQPs) are a family of more than 10 homologous water transporting proteins expressed in many mammalian epithelia and endothelia. At least five AQPs are expressed in the eye: AQP0(MIP) in lens fiber, AQP1 in cornea endothelium, ciliary and lens epithelia and trabecular meshwork, AQP3 in conjunctiva, AQP4 in ciliary epithelium and retinal Müller cells, and AQP5 in corneal and lacrimal gland epithelia. Among the seven human aquaporins cloned to date(AQPs 0-6), genes encoding the four most closely related aquaporins(AQP0, AQP2, AQP5, and AQP6) have been mapped to chromosome band 12q13, suggesting an aquaporin family gene cluster at this locus. Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions.

Description:
Rabbit IgG polyclonal antibody for Aquaporin-5 (AQP5) detection. Tested with WB, IHC-P in Mouse, Rat.

Synonyms:
AQP 5 antibody, AQP-5 antibody, AQP5 antibody, AQP5_HUMAN antibody, Aquaporin 5 antibody, Aquaporin-5 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of mouse AQP5(246-265aa EEDWEDHREERKKTIELTAH), identical to the related rat sequence.A synthetic peptide corresponding to a sequence at the C-terminus of mouse AQP5(246-265aa EEDWEDHREERKKTIELTAH), identical to the related rat sequence.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: rat.
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.