ARAP1 Polyclonal Antibody

Background:
The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3, 4, 5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Area: Signal Transduction

Synonyms:
2410002L19Rik, ANK repeat and PH domain-containing protein 1, ARAP 1, Arap1, ARAP1, Arf GAP Rho GAP ankyrin repeat and pleckstrin homology domains containing protein 1, Arf GAP Rho GAP ankyrin repeat and pleckstrin homology domain containing protein 1, Arf-GAP with Rho-GAP domain, CENT D2, Centaurin delta 2, Centaurin delta2, Centaurin-delta-2, CENTD 2, CENTD2, Cnt d2, Cnt-d2, Cntd2, KIAA0782, MGC176140, mKIAA0782

Immunogen: Synthetic peptide of human ARAP1

Swissprot: Q96P48
Gene Accession: NP_001035207

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 1 mg/mL
Dilution: IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-47799/sc-47796