ARC polyclonal antibody, anti-human, mouse, rat

Background:
Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors.,Belongs to the ARC/ARG3.1 family.,subcellular location:Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail.,subunit:Interacts with SH3GL1/endophilin-2, SH3GL3/endophilin-3 and DNM2/DYN2.,

Research Area: Neuroscience, Tags & cell markers

Synonyms: Activity-regulated cytoskeleton-associated protein , ARC/ARG3.1, Activity-regulated gene 3.1 protein homolog, Arg3.1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year