ARFGAP1 polyclonal, anti-human, mouse

Background:
The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms: ARF1GAP, HRIHFB2281

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human ARFGAP1

Gene Symbol: ARFGAP1

Gene ID: 55738

Swiss prot: Q8N6T3

Calculated MW: 45kDa

Recommended dilution:
WB 1:1000-5000, IHC 1:25-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.