ARFGAP3 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP14517b
Catalog Number: AC-AP14517b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34320
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34320
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.
Other Names:
ADP-ribosylation factor GTPase-activating protein 3, ARF GAP 3, ARFGAP3, ARFGAP1
Target/Specificity:
This ARFGAP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-473 amino acids from the C-terminal region of human ARFGAP3.
Antigen Region:
445-473
Antigen Type: Synthetic Peptide
Gene Name: ARFGAP3
Gene ID: 26286
Primary Accession: Q9NP61
NCBI Accession: NP_001135765.1;NP_055385.3
Other Accession: NP_001135765.1;NP_055385.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.
Other Names:
ADP-ribosylation factor GTPase-activating protein 3, ARF GAP 3, ARFGAP3, ARFGAP1
Target/Specificity:
This ARFGAP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-473 amino acids from the C-terminal region of human ARFGAP3.
Antigen Region:
445-473
Antigen Type: Synthetic Peptide
Gene Name: ARFGAP3
Gene ID: 26286
Primary Accession: Q9NP61
NCBI Accession: NP_001135765.1;NP_055385.3
Other Accession: NP_001135765.1;NP_055385.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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