ARFGEF1 Polyclonal Antibody

Background:
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP. It contains a Sec7 domain, which may be responsible for guanine-nucleotide exchange activity and also brefeldin A inhibition.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Signal transduction, Tags & Cell Markers

Synonyms:
ADP ribosylation factor guanine nucleotide exchange factor 1(brefeldin A inhibited), ADP-ribosylation factor guanine nucleotide exchange factor 1, ARF GEP1, ARFGEF1, ARFGEP1, Brefeldin A inhibited GEP 1, Brefeldin A inhibited guanine nucleotide exchange protein 1, P200, p200 ARF guanine nucleotide exchange factor

Immunogen: Synthetic peptide of human ARFGEF1

Swissprot: Q9Y6D6
Gene Accession: NP006412

Calculated MW: 209 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.5 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.