ARGBP2 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP6997a
Catalog Number: AC-AP6997a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19714
Applications: WB, IF, IHC-P, FC
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19714
Applications: WB, IF, IHC-P, FC
Datasheet
Request Information
Background:
Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. ARGBP2 is the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology(SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton.
Other Names:
Sorbin and SH3 domain-containing protein 2, Arg/Abl-interacting protein 2, ArgBP2, Sorbin, SORBS2, ARGBP2, KIAA0777
Target/Specificity:
This ARGBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-204 amino acids from the N-terminal region of human ARGBP2.
Antigen Region:
175-204
Antigen Type: Synthetic Peptide
Gene Name: SORBS2
Gene ID: 8470
Primary Accession: O94875
NCBI Accession: NP_001139142.1;NP_001139143.1;NP_001139144.1;NP_001139145.1;NP_001139146.1;NP_001257700.1;NP_003594.3;NP_066547.1
Other Accession: O35413; P28220; Q3UTJ2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. ARGBP2 is the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology(SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton.
Other Names:
Sorbin and SH3 domain-containing protein 2, Arg/Abl-interacting protein 2, ArgBP2, Sorbin, SORBS2, ARGBP2, KIAA0777
Target/Specificity:
This ARGBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-204 amino acids from the N-terminal region of human ARGBP2.
Antigen Region:
175-204
Antigen Type: Synthetic Peptide
Gene Name: SORBS2
Gene ID: 8470
Primary Accession: O94875
NCBI Accession: NP_001139142.1;NP_001139143.1;NP_001139144.1;NP_001139145.1;NP_001139146.1;NP_001257700.1;NP_003594.3;NP_066547.1
Other Accession: O35413; P28220; Q3UTJ2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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