ARHGDIA polyclonal, anti-human, mouse, rat, monkey

Background:
This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants.

Synonyms: GDIA1, HEL-S-47e, NPHS8, RHOGDI, RHOGDI-1

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human ARHGDIA

Gene Symbol: ARHGDIA

Gene ID: 396

Swiss prot: P52565

Calculated MW: 23kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.