ARHGDIB Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13743b
Background:
Members of the Rho (or ARH) protein family (see MIM165390) and other Ras-related small GTP-binding proteins (see MIM179520) are involved in diverse cellular events, including cellsignaling, proliferation, cytoskeletal organization, and secretion.The GTP-binding proteins are active only in the GTP-bound state. Atleast 3 classes of proteins tightly regulate cycling between theGTP-bound and GDP-bound states: GTPase-activating proteins (GAPs),guanine nucleotide-releasing factors (GRFs), and GDP-dissociationinhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rateof GDP dissociation from Ras-like GTPases (summary by Scherle etal., 1993 [PubMed 8356058]).
Other Names:
Rho GDP-dissociation inhibitor 2, Rho GDI 2, Ly-GDI, Rho-GDI beta, ARHGDIB, GDIA2, GDID4, RAP1GN1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13743b was selected from the C-term region of ARHGDIB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: ARHGDIB
Gene ID: 397
Primary Accession: P52566
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Members of the Rho (or ARH) protein family (see MIM165390) and other Ras-related small GTP-binding proteins (see MIM179520) are involved in diverse cellular events, including cellsignaling, proliferation, cytoskeletal organization, and secretion.The GTP-binding proteins are active only in the GTP-bound state. Atleast 3 classes of proteins tightly regulate cycling between theGTP-bound and GDP-bound states: GTPase-activating proteins (GAPs),guanine nucleotide-releasing factors (GRFs), and GDP-dissociationinhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rateof GDP dissociation from Ras-like GTPases (summary by Scherle etal., 1993 [PubMed 8356058]).
Other Names:
Rho GDP-dissociation inhibitor 2, Rho GDI 2, Ly-GDI, Rho-GDI beta, ARHGDIB, GDIA2, GDID4, RAP1GN1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13743b was selected from the C-term region of ARHGDIB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: ARHGDIB
Gene ID: 397
Primary Accession: P52566
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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