ARHGEF7 polyclonal, anti-human, mouse, monkey

Background:
This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene.

Synonyms: BETA-PIX, COOL-1, COOL1, Nbla10314, P50, P50BP, P85, P85COOL1, P85SPR, PAK3, PIXB

Cellular Location: Cell junction Cell projection Cytoplasm cell cortex focal adhesion lamellipodium ruffle

Immunogen:
Recombinant protein of human ARHGEF7

Gene Symbol: ARHGEF7

Gene ID: 8874

Swiss prot: Q14155

Calculated MW: 90kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.