ARHGEF7 polyclonal (C-Term), anti-human, mouse
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In stock
SKU
AC-AP22153b
Catalog Number: AC-AP22153b
Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB56222
Applications: WB
Datasheet
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Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB56222
Applications: WB
Datasheet
Request Information
Background:
Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions (By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
Other Names:
Rho guanine nucleotide exchange factor 7, Beta-Pix, COOL-1, PAK-interacting exchange factor beta, p85, ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Target/Specificity:
This ARHGEF7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 654-688 amino acids from human ARHGEF7.
Antigen Type: Synthesized Peptide
Gene Name: ARHGEF7
Gene ID: 8874
Primary Accession: Q14155
Other Accession: Q9ES28
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions (By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
Other Names:
Rho guanine nucleotide exchange factor 7, Beta-Pix, COOL-1, PAK-interacting exchange factor beta, p85, ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Target/Specificity:
This ARHGEF7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 654-688 amino acids from human ARHGEF7.
Antigen Type: Synthesized Peptide
Gene Name: ARHGEF7
Gene ID: 8874
Primary Accession: Q14155
Other Accession: Q9ES28
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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