ARHGEF9 Polyclonal Antibody

Background:
The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.

Research Area: Signal Transduction

Synonyms:
9630036L12Rik, A230067K14, ARHG9, Arhgef9, Cdc42 guanine nucleotide exchange factor (GEF) 9, Collybistin, collybistin I, EIEE8, HPEM 2, hPEM-2 collybistin, KIAA0424, mKIAA0424, OTTHUMP00000023424, OTTHUMP00000023425, OTTHUMP00000023427, PEM 2, PEM 2 homolog, PEM-2 homolog, PEM2, Rac/Cdc42 guanine nucleotide exchange factor 9, Rho guanine nucleotide exchange factor 9, RP11 357C3.4, RP23 230K20.3

Immunogen: Recombinant protein of human ARHGEF9

Swissprot: O43307
Gene Accession: BC117406

Calculated MW: 61 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-167129