ARID1A polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
AT-rich interactive domain-containing protein 1A, also known as p270, is a protein that in humans is encoded by the ARID1A gene. This gene encodes a member of the SWI/SNF families, whose members have helicase and ATPase activities and are though to regulate transcription of certain genes by altering the chromatin structure around those genes. ARID1A is mapped to 1p36.11. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation.

Description:
Rabbit IgG polyclonal antibody for AT-rich interactive domain-containing protein 1A (ARID1A) detection. Tested with WB, IHC-P, ICC in Human, Mouse, Rat.

Synonyms:
actin-dependent regulator of chromatin subfamily F member 1 antibody, ARI1A_HUMAN antibody, ARID domain containing protein 1A antibody, ARID domain-containing protein 1A antibody, ARID1A antibody, AT rich interactive domain 1A(SWI like) antibody, AT rich interactive domain 1A antibody, AT rich interactive domain containing protein 1A antibody, AT-rich interactive domain-containing protein 1A antibody, B120 antibody, BAF250 antibody, BAF250A antibody, BM029 antibody, brain protein 120 antibody, BRG1 associated factor 250 antibody, BRG1 associated factor 250a antibody, BRG1-associated factor 250 antibody, BRG1-associated factor 250a antibody, C1ORF4 antibody, chromatin remodeling factor p250 antibody, chromosome 1 open reading frame 4 antibody, hELD antibody, hOSA1 antibody, matrix-associated antibody, Osa homolog 1 antibody, OSA1 antibody, OSA1 nuclear protein antibody, P270 antibody, SMARCF1 antibody, SWI like protein antibody, SWI SNF complex protein p270 antibody, SWI-like protein antibody, SWI/SNF complex protein p270 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily f, member 1 antibody, SWI/SNF-related antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human ARID1A(2199-2213aa LEDSLAATQFQQSQA), identical to the related mouse and rat sequences.A synthetic peptide corresponding to a sequence at the C-terminus of human ARID1A(2199-2213aa LEDSLAATQFQQSQA), identical to the related mouse and rat sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P, ICC

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.