ARID1A polyclonal, anti-human, mouse, rat

Background:
The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2α) and Brg-1 (also designated SNF2β) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits, such as BAF250a (p270 or ARID 1A) and BAF250b(ARID1B), are thought to play regulatory roles.

Alternative Name:
ARID domain-containing protein 1A, BAF250, BAF250A, hOSA1, ARID1A, actin-dependent regulator of chromatin subfamily F member 1, ARI1A, ARID domain containing protein 1A, ARID domain-containing protein 1A, ARID1A, AT rich interactive domain 1A (SWI like), AT rich interactive domain 1A, AT rich interactive domain containing protein 1A, AT-rich interactive domain-containing protein 1A, B120, BAF250, BAF250A, BM029, brain protein 120, BRG1 associated factor 250, BRG1 associated factor 250a, BRG1-associated factor 250, BRG1-associated factor 250a, C1ORF4, chromatin remodeling factor p250, chromosome 1 open reading frame 4, ELD, hELD, hOSA1, matrix-associated, MRD14, Osa homolog 1, OSA1, OSA1 nuclear protein, P270, SMARCF1, SWI like protein, SWI SNF complex protein p270, SWI-like protein, SWI/SNF complex protein p270, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily f, member 1, SWI/SNF-related,

Application Dilution:
ICC:1:50-1:200
IHC:1:50-1:200

Specificity: ARID1A polyclonal antibody detects endogenous levels of ARID1A protein.

Immunogen:
recombinant protein

Swiss-Prot: O14497(Human) A2BH40(Mouse) Unigene:61077(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.